A DISTAL INTERGENIC REGION CONTROLS PANCREATIC ENDOCRINE DIFFERENTIATION BY ACTING AS A TRANSCRIPTIONAL ENHANCER AND AS A POLYCOMB RESPONSE ELEMENT.

A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element.

Lineage-selective expression of developmental genes is dependent on the interplay between activating and repressive mechanisms.Gene activation is dependent on cell-specific transcription factors that recognize transcriptional enhancer sequences.Gene repression often depends on the recruitment of Polycomb group (PcG) proteins, although the sequences

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SPACES as a Counseling Approach in Treating Traumatic Experiences of the Typhoon Sendong Victims in Iligan City, Philippines

The creation of a counseling approach for Filipinos remains a big challenge to counselors.Foreign counseling methods do not meet the needs of Filipino clients in addressing diverse issues.Moreover, different regions have different perspectives as far as problems, etiology, manifestations and solutions are concerned.The study aimed to show that SPAC

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LAUGH, NOT WAR: HUMOR, SATIRE AND THE DISSOLUTION OF YUGOSLAVIA

The article presents a concise review of Repellents political criticism through the medium of humor and satire, at the time of ex-Yugoslavia and during its dissolution.It covers several important magazines and individual authors from ex-Yugoslav republics that, in difficult times for the freedom of speech, have shown dignity and courage to describe

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Improving the Speed of Small Deep Hole Electrical Discharge Machining by Combining Rotation of the Electrode with a Rapid-Response

In this paper, we report on the co-operative control of a 5-DOF controlled magnetically-levitated (maglev) local actuator Cleansing Foam (MLA) combined with a conventional electrical discharge machine, which we developed as a means to increasing the electrical discharge machining (EDM) speed for small deep holes.The MLA enables the electrode to be

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